FMP

• Target :

  ROS|||Apoptosis|||Reactive Oxygen Species|||PARP|||Caspase|||Bcl-2 Family|||MDM-2/p53

• Related Pathways :

  Proteases/Proteasome|||Apoptosis|||DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Metabolism|||Immunology/Inflammation|||NF-?B

• Bioactivity :

  FMP is a platinum (IV) complex. It significantly upregulates the expression of ?-H2AX and p53, enhances ROS production, and markedly increases the expression of apoptosis (Apoptosis) related proteins (DR5, Fas, caspase-8, Cyt-c, caspase-3, cleaved-PARP1, Bax) . FMP exhibits antiproliferative activity against breast cancer.

• Molecular Formula :

  C18H18Cl2N2O7Pt

• Molecular Weight :

  640.33

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C