FMP

CAT: 0931-T205455-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205455-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
ROS|||Apoptosis|||Reactive Oxygen Species|||PARP|||Caspase|||Bcl-2 Family|||MDM-2/p53
Related Pathways
Proteases/Proteasome|||Apoptosis|||DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Metabolism|||Immunology/Inflammation|||NF-?B
Bioactivity
FMP is a platinum (IV) complex. It significantly upregulates the expression of ?-H2AX and p53, enhances ROS production, and markedly increases the expression of apoptosis (Apoptosis) related proteins (DR5, Fas, caspase-8, Cyt-c, caspase-3, cleaved-PARP1, Bax) . FMP exhibits antiproliferative activity against breast cancer.
Molecular Formula
C18H18Cl2N2O7Pt
Molecular Weight
640.33
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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