API-1

CAT: 0931-T8969-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T8969-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

36707-00-3

Target

Apoptosis, PARP, Caspase, Akt

Related Pathways

Cytoskeletal Signaling, Proteases/Proteasome, Chromatin/Epigenetic, Apoptosis, DNA Damage/DNA Repair, PI3K/Akt/mTOR signaling

Purity

0.9907

Bioactivity

API-1 (NSC-177223) is a potent inhibitor of Akt. It induces GSK3-dependent, β-TrCP- and FBXW7-mediated Mcl-1 degradation, resulting in induction of apoptosis .

Smiles

NC(=O)c1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2ncnc(N)c2c1=O

Molecular Formula

C13H15N5O6

Molecular Weight

337.29

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
406398	API-1
A22093-5	API-1 5mg
HY-W288951-01	FMP-API-1
A22093-100	API-1 100mg
A22093-1	API-1 1mg
GTR19348569-01	Api g 1
A22093-200	API-1 200mg
A22093-25	API-1 25mg
A22093-50	API-1 50mg
A22093-10	API-1 10mg

API-1

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