BMS-818251

• Target:

  HIV Protease

• Related Pathways:

  Microbiology/Virology|||Proteases/Proteasome

• Bioactivity:

  BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved ?20-?21 hairpin.

• Smiles:

  N#CC(C=1C=CC=CC1)=C2CCN(C(=O)C(=O)C3=CNC4=C(N=CC(OC)=C34)C=5N=C(SC5)C(=O)NCCO)CC2

• Molecular Formula:

  C29H26N6O5S

• Molecular Weight:

  570.619

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2974489-09-1