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BMS-818251

CAT: 0931-T204307-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T204307-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2974489-09-1
Target
HIV Protease
Related Pathways
Microbiology/Virology, Proteases/Proteasome
Bioactivity
BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.
Smiles
N#CC(C=1C=CC=CC1)=C2CCN(C(=O)C(=O)C3=CNC4=C(N=CC(OC)=C34)C=5N=C(SC5)C(=O)NCCO)CC2
Molecular Formula
C29H26N6O5S
Molecular Weight
570.619
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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