ABCG2-IN-4

CAT: 0931-T204144-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T204144-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2559759-63-4
Target
BCRP
Related Pathways
Membrane transporter/Ion channel
Bioactivity
ABCG2-IN-4 (Compound K31) is an orally active ABCG2 inhibitor that reduces the release of Protoporphyrin IX (PPIX) from red blood cells into the plasma and prevents phototoxicity. In mouse models, ABCG2-IN-4 also demonstrates anti-inflammatory and antioxidant properties.
Smiles
C(C(C)C)[C@H]1C2=C(C=3C(N2)=CC(OC)=CC3)C[C@@]4(N1C(=O)[C@H](CC(NC(C)C)=O)NC4=O)[H]
Molecular Formula
C24H32N4O4
Molecular Weight
440.535
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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