ABCG2-IN-4

• Target:

  BCRP

• Related Pathways:

  Membrane transporter/Ion channel

• Bioactivity:

  ABCG2-IN-4 (Compound K31) is an orally active ABCG2 inhibitor that reduces the release of Protoporphyrin IX (PPIX) from red blood cells into the plasma and prevents phototoxicity. In mouse models, ABCG2-IN-4 also demonstrates anti-inflammatory and antioxidant properties.

• Smiles:

  C(C(C)C)[C@H]1C2=C(C=3C(N2)=CC(OC)=CC3)C[C@@]4(N1C(=O)[C@H](CC(NC(C)C)=O)NC4=O)[H]

• Molecular Formula:

  C24H32N4O4

• Molecular Weight:

  440.535

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2559759-63-4