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PARL-IN-2

CAT: 0931-T203239-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T203239-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Mitophagy, PTEN
Related Pathways
Autophagy, PI3K/Akt/mTOR signaling
Bioactivity
PARL-IN-2 (Compound 14) is a covalent inhibitor of the mitochondrial inner membrane protease PARL, with an EC50 value of 0.16 μM. It strongly activates the PINK1/Parkin pathway and enhances PINK1/Parkin-dependent mitophagy.
Molecular Formula
C22H23NO4
Molecular Weight
365.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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