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Zotiraciclib citrate

CAT: 0931-T202626-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T202626-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1204918-73-9
Bioactivity
Zotiraciclib (also known as TG02 and SB1317) is an innovative small-molecule compound with potent inhibitory effects on CDK, JAK2, and FLT3. By inhibiting cyclin-dependent kinase 9 (CDK9) and depleting Myc, it serves as a treatment for cancers that can penetrate the blood-brain barrier. Zotiraciclib is one of the numerous CDK inhibitors under investigation; other compounds targeting CDK9, utilized for treating acute myeloid leukemia, include alvocidib and atuveciclib. Myc overexpression is a known factor in many cancers, with 80% of glioblastomas exhibiting this characteristic.
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Molecular Formula
C29H32N4O8
Molecular Weight
564.59
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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