(E/Z) -Zotiraciclib

• Target:

  JAK|||FLT|||CDK

• Related Pathways:

  Chromatin/Epigenetic|||Cell Cycle/Checkpoint|||JAK/STAT signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Stem Cells

• Purity:

  0.9992

• Bioactivity:

  (E/Z) -Zotiraciclib ((E/Z) -TG02) effectively inhibits CDK2, JAK2, and FLT3 with IC50s of 13 nM, 73 nM, and 56 nM, respectively.

• Smiles:

  CN1CC2=CC(N=C3NC(C=4C=C(C=CC4)OCCC=CC1)=CC=N3)=CC=C2

• Molecular Formula:

  C23H24N4O

• Molecular Weight:

  372.46

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  937270-47-8