TPI-1020

• Bioactivity:

  TPI-1020 is a novel anti-inflammatory corticosteroid and nitric oxide (NO) donor derived from budesonide. It exhibits a concentration-dependent bronchodilatory effect mediated by released NO through a cGMP-dependent pathway. Studies suggest that TPI-1020 combines corticosteroid activity with NO release, potentially benefiting the treatment of acute bronchoconstriction events in asthma and allowing for a reduced dose of inhaled beta (2) -adrenoceptor agonists.

• Smiles:

  O=C(C1=CC=C(C=C1)CO[N+]([O-])=O)OCC([C@]23[C@@]4([C@@]([C@@]5([H])[C@]([C@@]6(C(CC5)=CC(C=C6)=O)C)([H])[C@H](C4)O)([H])C[C@@]2([H])OC(O3)CCC)C)=O

• Molecular Formula:

  C33H39NO10

• Molecular Weight:

  609.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  571186-52-2