TPI-1020

• Bioactivity:

  TPI-1020 is a novel anti-inflammatory corticosteroid and nitric oxide (NO) donor derived from budesonide. It exhibits a concentration-dependent bronchodilatory effect mediated by released NO through a cGMP-dependent pathway. Studies suggest that TPI-1020 combines corticosteroid activity with NO release, potentially benefiting the treatment of acute bronchoconstriction events in asthma and allowing for a reduced dose of inhaled beta (2) -adrenoceptor agonists.

• Smiles:

  O=C (C1=CC=C (C=C1) CO[N+] ([O-]) =O) OCC ([C@]23[C@@]4 ([C@@] ([C@@]5 ([H]) [C@] ([C@@]6 (C (CC5) =CC (C=C6) =O) C) ([H]) [C@H] (C4) O) ([H]) C[C@@]2 ([H]) OC (O3) CCC) C) =O

• Molecular Formula:

  C33H39NO10

• Molecular Weight:

  609.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  571186-52-2