TPI-287

• Target :

  Others|||Microtubule Associated

• Related Pathways :

  Cytoskeletal Signaling|||Others

• Bioactivity :

  TPI 287 is a synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis.

• Smiles :

  O(C(C)=O)[C@]12[C@@]3([C@]4(C)[C@]([C@@H](OC(C)=O)C=5C(C)(C)[C@](O)([C@H]3OC(=O)C6=CC=CC=C6)C[C@H](OC([C@@H]([C@@H](NC(OC(C)(C)C)=O)CC(C)C)O)=O)C5C)(OC(C=C)O[C@]4(C[C@]1(OC2)[H])[H])[H])[H]

• Molecular Formula :

  C46H63NO15

• Molecular Weight :

  869.99

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  849213-15-6