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TPI-287

CAT: 0931-T68570-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T68570-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
849213-15-6
Target
Others, Microtubule Associated
Related Pathways
Cytoskeletal Signaling, Others
Bioactivity
TPI 287 is a synthetic, third generation taxane with potential antineoplastic activity. TPI 287 binds to tubulin and stabilizes microtubules, resulting in inhibition of microtubule assembly/disassembly dynamics, cell cycle arrest at the G2/M phase, and apoptosis.
Smiles
O(C(C)=O)[C@]12[C@@]3([C@]4(C)[C@]([C@@H](OC(C)=O)C=5C(C)(C)[C@](O)([C@H]3OC(=O)C6=CC=CC=C6)C[C@H](OC([C@@H]([C@@H](NC(OC(C)(C)C)=O)CC(C)C)O)=O)C5C)(OC(C=C)O[C@]4(C[C@]1(OC2)[H])[H])[H])[H]
Molecular Formula
C46H63NO15
Molecular Weight
869.99
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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