MS-1020

• Target:

  JAK|||Others

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Others|||Chromatin/Epigenetic|||Angiogenesis|||Stem Cells|||JAK/STAT signaling

• Bioactivity:

  MS-1020 is a JAK3 and STAT3 inhibitor. MS-1020 selectively blocks constitutively-active JAK3 and consistently suppressed interleukin-2-induced JAK3/STAT5 signalling. MS-1020 potently inhibits persistently-active STAT3 in a cell type-specific manner.

• Smiles:

  C(CNC(=O)C1=C(O)C2=C(C=C1)C=CC=C2)C=3C=4C(NC3)=CC=C(O)C4

• Molecular Formula:

  C21H18N2O3

• Molecular Weight:

  346.38

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1255516-86-9