MS-1020

CAT: 0931-T28113Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T28113Size:1 mg

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CAS Number

1255516-86-9

Target

JAK, Others

Related Pathways

Tyrosine Kinase/Adaptors, Others, Chromatin/Epigenetic, Angiogenesis, Stem Cells, JAK/STAT signaling

Bioactivity

MS-1020 is a JAK3 and STAT3 inhibitor. MS-1020 selectively blocks constitutively-active JAK3 and consistently suppressed interleukin-2-induced JAK3/STAT5 signalling. MS-1020 potently inhibits persistently-active STAT3 in a cell type-specific manner.

Smiles

C(CNC(=O)C1=C(O)C2=C(C=C1)C=CC=C2)C=3C=4C(NC3)=CC=C(O)C4

Molecular Formula

C21H18N2O3

Molecular Weight

346.38

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

1-Hydroxy-N-[2-(5-hydroxy-1H-indol-3-YL)ethyl]naphthalene-2-carboxamide

CAS Number	1255516-86-9
PubChem CID	73438566
IUPAC Name	1-hydroxy-N-[2-(5-hydroxy-1H-indol-3-yl)ethyl]naphthalene-2-carboxamide
Molecular Formula	C21H18N2O3
Molecular Weight	346.4
XLogP	4.4
Topological Polar Surface Area	85.4
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Heavy Atom Count	26
Formal Charge	0
Complexity	500

SMILES

C1=CC=C2C(=C1)C=CC(=C2O)C(=O)NCCC3=CNC4=C3C=C(C=C4)O

InChI

InChI=1S/C21H18N2O3/c24-15-6-8-19-18(11-15)14(12-23-19)9-10-22-21(26)17-7-5-13-3-1-2-4-16(13)20(17)25/h1-8,11-12,23-25H,9-10H2,(H,22,26)

InChIKey

KHJNISGKGIHTMY-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1255516-86-9

CID: 73438566

Formula: C21H18N2O3

MW: 346.4

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	346.4
XLogP3	4.4
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	4
Exact Mass	346.13174244
Monoisotopic Mass	346.13174244
Topological Polar Surface Area	85.4 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	500
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T22663-01	CI 1020
T202615-01	TPI-1020
T60377-01	CXL-1020
T16151-01	Ms-PEG7-Ms
T16148-01	Ms-PEG2-Ms
T38491-01	Ms-PEG6-Ms
T16149-01	Ms-PEG4-Ms
T26834-01	BL-1020 Mesylate
T202458-01	MS-8709
T41291-01	MS-PPOH

Alternative Products

Catalog	Name
FAC51686-01	MS-1020
HY-147384	CXL-1020
268573-01	CI 1020
MBS3604709	BL-1020
HY-103459	CI-1020
GTR19241921-01	TPI-1020
BUP03313-01	BL-1020 Mesylate
WDC60245-01	CI 1020-d9
50110-1	PCL-1020 Cartridge
HY-111136-01	BL-1020 (mesylate)

MS-1020

Chemical Information

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