AO-176

CAT: 0931-MF-0062909-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0062909-01Size:1 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2691109-74-5
Target
Others
Related Pathways
Others
Bioactivity
AO-176 is a humanized anti-CD47 IgG2 monoclonal antibody. It induces tumor phagocytosis by blocking the interaction between CD47 and SIRP?. AO-176 preferentially binds to tumor cells over normal cells and directly kills tumor cells through a cell-autonomous mechanism, rather than via antibody-dependent cellular cytotoxicity (ADCC) . In tumor xenograft models, AO-176 demonstrates dose-dependent antitumor activity. This compound is applicable in cancer research, such as studies involving lymphoma.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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