DS-003

• Bioactivity :

  DS-003 is a small molecule Gp120 inhibitor. As an analog of BMS-378806, DS003 demonstrates enhanced inhibitory activity during prolonged exposure and when used in combination with fusion inhibitors. However, prior exposure to soluble CD4+ hinders DS003's binding to the viral envelope. Studies indicate that due to its targeting of the CD4+ binding site on Gp120, DS003 is a promising candidate for pre-exposure prophylactic therapy.

• Smiles :

  N#CC(C=1C=CC=CC1)=C2CCN(C(=O)C(=O)C3=CNC=4C(=NC=C(OC)C34)C=5N=CC=NC5)CC2

• Molecular Formula :

  C27H22N6O3

• Molecular Weight :

  478.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  676489-50-2