DS-003

CAT: 0931-T202020-01Size: 10 mgDry Ice: NoHazardous: No

CAT#:0931-T202020-01Size:10 mg

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AVAILABILITY

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

676489-50-2

Bioactivity

DS-003 is a small molecule Gp120 inhibitor. As an analog of BMS-378806, DS003 demonstrates enhanced inhibitory activity during prolonged exposure and when used in combination with fusion inhibitors. However, prior exposure to soluble CD4+ hinders DS003's binding to the viral envelope. Studies indicate that due to its targeting of the CD4+ binding site on Gp120, DS003 is a promising candidate for pre-exposure prophylactic therapy.

Smiles

N#CC(C=1C=CC=CC1)=C2CCN(C(=O)C(=O)C3=CNC=4C(=NC=C(OC)C34)C=5N=CC=NC5)CC2

Molecular Formula

C27H22N6O3

Molecular Weight

478.5

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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