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PROTAC K-Ras Degrader-6

CAT: 0931-T201811-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T201811-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3052745-46-4
Target
PROTACs, Ras, Antibacterial
Related Pathways
Microbiology/Virology, MAPK, GPCR/G Protein, PROTAC
Bioactivity
Pan-KRAS degrader 5 (compound 102) is a cereblon-based PROTAC KRAS degrader with a DC50 value less than 100 nM, exhibiting anticancer activity.
Smiles
O=C1NC(=O)C(N2C(=O)N(C3=CC(=CC=C32)N4CCC(CN5CCC(CC5)CC6CCN(CCOC7=NC8=C(F)C(=NC=C8C(=N7)N9CC%10NC(C9)CC%10)C=%11C=C(O)C=C%12C=CC(F)=C(C#C)C%12%11)CC6)CC4)C)CC1
Molecular Formula
C57H65F2N11O5
Molecular Weight
1022.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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