MG-T-19

CAT: 0931-T201721-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T201721-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

328540-44-9

Target

Immunology/Inflammation related

Related Pathways

Immunology/Inflammation

Purity

0.9914

Bioactivity

MG-T-19, a TIM-3 inhibitor (KD=0.26 μM), significantly inhibited the interaction of TIM-3 with PtdSer, CEACAM1, and Gal-9, and increased the production of TNF-α and IFN-γ in PBMCs, which reactivated the tumor-attacking ability of T cells.

Smiles

O=C(NC1=CC(Cl)=CC=C1O)C2=NN3C(N=C(C=C3C(F)(F)F)C=4SC=C(Br)C4)=C2Br

Molecular Formula

C18H8Br2ClF3N4O2S

Molecular Weight

596.6

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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MG-T-19

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