MG-132

• Target:

  Apoptosis|||Proteasome|||Autophagy

• Related Pathways:

  Apoptosis|||Autophagy|||Ubiquitination|||Proteases/Proteasome

• Purity:

  0.9999

• Bioactivity:

  MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor (IC50=100 nM) that is cell-permeable and reversible. MG-132 acts as an autophagy activator and also induces apoptosis.

• Smiles:

  CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCc1ccccc1)C=O

• Molecular Formula:

  C26H41N3O5

• Molecular Weight:

  475.62

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  133407-82-6