STAT3-IN-36

• Target:

  STAT|||GluR

• Related Pathways:

  JAK/STAT signaling|||Neuroscience|||Stem Cells

• Bioactivity:

  STAT3-IN-36 (compound 11g) is a tritarget inhibitor that selectively targets LRPPRC, STAT3, and CDK1, exhibiting potent anticancer activity. This compound binds to LRPPRC, STAT3, and CDK1, demonstrating more effective anticancer effects than those of TMF or Capecitabine. Additionally, STAT3-IN-36 exhibits an IC50 value of 1.8 ?M in HGC27 cells.

• Smiles:

  O=C1C=C(OC=2C1=C(OC)C=C(OC)C2S(=O)(=O)NC3=CC=C(F)C=C3)C=4C=CC(OC)=C(C4)S(=O)(=O)NC5=CC=C(F)C=C5

• Molecular Formula:

  C30H24F2N2O9S2

• Molecular Weight:

  658.65

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3055766-74-7