KY-05009

• Target :

  MAPK|||Apoptosis|||Wnt/beta-catenin

• Related Pathways :

  Cytoskeletal Signaling|||Stem Cells|||MAPK|||Apoptosis

• Purity :

  0.9989

• Bioactivity :

  KY-05009 is a chemical compound that effectively suppresses TGF-?1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity of Wnt target genes, and promotes apoptosis in cancer cells, displaying anti-cancer properties. Furthermore, it functions as an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM.

• Smiles :

  Cc1ccc(cc1)C(=O)Nc1sc(Nc2ccccc2)nc1C(N)=O

• Molecular Formula :

  C18H16N4O2S

• Molecular Weight :

  352.41

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1228280-29-2