KY-05009

• Target:

  MAPK|||Apoptosis|||Wnt/beta-catenin

• Related Pathways:

  Cytoskeletal Signaling|||Stem Cells|||MAPK|||Apoptosis

• Purity:

  0.9989

• Bioactivity:

  KY-05009 is a chemical compound that effectively suppresses TGF-?1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells, reduces TNIK protein expression and the transcriptional activity of Wnt target genes, and promotes apoptosis in cancer cells, displaying anti-cancer properties. Furthermore, it functions as an ATP-competitive Traf2- and Nck-interacting kinase (TNIK) inhibitor with a Ki of 100 nM.

• Smiles:

  Cc1ccc (cc1) C (=O) Nc1sc (Nc2ccccc2) nc1C (N) =O

• Molecular Formula:

  C18H16N4O2S

• Molecular Weight:

  352.41

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1228280-29-2