AK-1690

• Target:

  PROTACs|||STAT

• Related Pathways:

  JAK/STAT signaling|||PROTAC|||Stem Cells

• Purity:

  >99.99%

• Bioactivity:

  AK-1690 is a potent and selective STAT6 PROTAC degrader that induces degradation of STAT6 proteins in cells (DC50=1 nM) and depletes STAT6 proteins in mouse tissues, which can be used in cancer research.

• Smiles:

  C (#CCCCCCO[C@H]1C[C@@H] (C (=O) N2C[C@H] (OCC2) C3=CC=CC=C3) N (C ([C@@H] (NC (=O) C4=CC=5C (S4) =CC=C (C (P (=O) (O) O) (F) F) C5) [C@@] (C) (C) C) =O) C1) C6=C7C (C (=O) N (C7) C8C (=O) NC (=O) CC8) =CC=C6

• Molecular Formula:

  C51H56F2N5O11PS

• Molecular Weight:

  1016.05

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2984505-88-4