AK-1

• Target:

  Sirtuin

• Related Pathways:

  Chromatin/Epigenetic|||DNA Damage/DNA Repair

• Purity:

  0.9944

• Bioactivity:

  AK-1 is a sirtuin 2 (SIRT2) inhibitor (IC50:12.5 ?M) .that prevents hippocampal neurodegeneration in Alzheimer's disease models and induces cell cycle arrest in colon carcinoma cells.

• Smiles:

  [O-][N+](=O)c1cccc(NC(=O)c2cccc(c2)S(=O)(=O)N2CCCCCC2)c1

• Molecular Formula:

  C19H21N3O5S

• Molecular Weight:

  403.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  330461-64-8