CDX2 Antibody [CDX2/1690]

• Background:

  The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

• NCBI Gene ID:

  1045

• Swiss Prot:

  Q99626

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Amino acids 150-249 from the human protein were used as the immunogen for this CDX2 antibody.

• Clonality:

  Monoclonal

• Clone:

  CDX2/1690

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Homeostasis, Stem Cell

• Purification:

  Protein G affinity chromatography

• Concentration:

  0.2 mg/mL

• Buffer:

  PBS with 0.1 mg/ml BSA and 0.05% sodium azide

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Aliquot and Store at 2-8˚ C. Avoid freez-thaw cycles.

• Fragment:

  IgG2a, kappa

• Symbol:

  CDX2

• NCBI Official Name:

  Caudal type homeobox 2

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CDX2 Antibody: CDX3, CDX-3, CDX3, Homeobox protein CDX-2

• Tested Applications:

  WB, IHC-P, Flow, IF

• Physical Properties:

  Liquid