PRMT5-IN-45
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PRMT5-IN-45
Target :
Apoptosis|||Histone MethyltransferaseRelated Pathways :
Chromatin/Epigenetic|||ApoptosisBioactivity :
PRMT5-IN-45 (compound 36) is a potent and selective inhibitor of PRMT5, exhibiting an IC50 value of 3 nM. This compound effectively reduces the levels of symmetrical dimethylarginine (sDMA) and inhibits the proliferation of the MOLM-13 cell line by inducing apoptosis and causing cell cycle arrest.Molecular Formula :
C26H31N7O2Molecular Weight :
473.57Shipping Conditions :
Cool packStorage Temperature :
-20°C
