JMS-175-2

• Target :

  DUB

• Related Pathways :

  DNA Damage/DNA Repair|||Ubiquitination|||Cell Cycle/Checkpoint

• Bioactivity :

  JMS-175-2 is an effective inhibitor of the BRCC36 isopeptidase complex (BRISC), exhibiting an IC50 of 3.8 ?M. This compound plays a crucial role in diseases mediated by Type I interferon.

• Smiles :

  O=C(NC1CCNCC1)C2=NN(C=C2NC(=O)C=3C(Cl)=CC=CC3Cl)C(=O)C=4C(Cl)=CC=CC4Cl

• Molecular Formula :

  C23H19Cl4N5O3

• Molecular Weight :

  555.24

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3042887-70-4