JMS-17-2 (hydrochloride)
CAT:
804-HY-123918A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
JMS-17-2 (hydrochloride)
- CAS Number: 2341841-07-2
- UNSPSC Description: JMS-17-2 hydrochloride is a potent and selective CX3CR1 antagonist with an IC50 of 0.32 nM. JMS-17-2 hydrochloride impairs metastatic seeding and colonization of breast cancer cells[1].
- Target Antigen: CX3CR1
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: Metabolism-protein/nucleotide metabolism
- Field of Research: Cancer; Endocrinology
- Assay Protocol: https://www.medchemexpress.com/jms-17-2-hydrochloride.html
- Solubility: 10 mM in DMSO
- Smiles: O=C1C2=CC=CN2C3=C(C=CC=C3)N1CCCN4CCC(C5=CC=C(Cl)C=C5)CC4.[H]Cl
- Molecular Weight: 456.41
- References & Citations: [1]Shen F, et al. Novel Small-Molecule CX3CR1 Antagonist Impairs Metastatic Seeding and Colonization of Breast Cancer Cells. Mol Cancer Res. 2016 Jun;14(6):518-27.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported