NOX2-IN-2

• Target:

  Others|||NADPH

• Related Pathways:

  Others|||Metabolism

• Bioactivity:

  NOX2-IN-2 (compound 33) is a potent inhibitor of NOX2, disrupting the p47phox-p22phox protein-protein interaction with a dissociation constant (Ki) of 0.24 ?M, and effectively suppressing reactive oxygen species (ROS) production from NOX2 in cellular contexts [1].

• Smiles:

  N1=NN(C=C1COC=2C=CC3=NC(N)=CC=C3C2)CCOCCOC=4C=CC5=NC(N)=CC=C5C4

• Molecular Formula:

  C25H25N7O3

• Molecular Weight:

  471.51

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2648709-79-7