Products for Research Use Only
RegisterLogin

P53-MDM2-IN-6

CAT: 0931-T200473-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T200473-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
1054506-59-0
Target
MDM-2/p53, Apoptosis
Related Pathways
Apoptosis
Bioactivity
P53-MDM2-IN-6, an LSM-83177 hydrazone analog, acts as an efficacious p53-MDM2 inhibitor with an IC50 of 11.08 μg/mL. This compound inhibits the p53-MDM2 interaction leading to an increase in p-53 levels while concurrently decreasing GST enzyme expression. It halts the cell cycle at the S phase and induces early and late apoptosis (Apoptosis), exhibiting antiproliferative activity against the HT29 cell line with an IC50 of 10.44 μg/mL. p53-MDM2-IN-6 holds promise for research in colorectal cancer.
Smiles
O=C(O)COC1=CC=C(C=NNC(=O)CNC=2C=CC=CC2)C=C1
Molecular Formula
C17H17N3O4
Molecular Weight
327.33
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T86876-01MDM2-p53-IN-18
T88309-01P53-MDM2-IN-5
T72026-01P53-MDM2-IN-1
T209225-01P53-MDM2-IN-2
T86877-01MDM2-p53-IN-20
T24440-01MDM2-p53-IN-1b
T72832-01MDM2-p53-IN-16
T200825-01P53-MDM2-IN-7 hydrochloride
T67698-01P53-Mdm2 inhibitor 4
T74936-01MDM2/4-p53-IN-3

Alternative Products

CatalogName
HY-162927P53-MDM2-IN-6
BA3476-10p53-MDM2-IN-1
BA3473-5MDM2-p53-IN-16
HY-121893-01P53-MDM2-IN-3
GTR19261866-01P53-MDM2-IN-2
HY-163661P53-MDM2-IN-5
MBS5774192MDM2-p53-IN-1b
GTR19234988-01MDM2-p53-IN-20
HY-161039MDM2-p53-IN-18
HY-W340313-01P53-MDM2-IN-4

Popular Products