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BSO-07

CAT: 0931-T200451-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200451-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
JNK, Reactive Oxygen Species
Related Pathways
Immunology/Inflammation, Metabolism, NF-κB, MAPK
Bioactivity
BSO-07 is a ROS/JNK activator that exhibits potent anti-cancer properties, demonstrated by an IC50 of 24.81 μM in human breast cancer (BC) cells. The mechanism of action for BSO-07 involves JNK activation and the promotion of increased ROS levels, which lead to the induction of apoptosis (Apoptosis) and tumorigenic apoptosis. This includes enhanced expression of apoptosis-related proteins such as PARP, Bax, phosphorylated p53, ATF4, and CHOP, along with a reduction in the levels of anti-apoptotic proteins (e.g., Bcl-2, Bcl-xL, and Survivin) . BSO-07 holds promise for research in the field of breast cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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