SD-7300

• Target :

  MMP

• Related Pathways :

  Proteases/Proteasome

• Bioactivity :

  SD-7300 (SC-81490) functions as an orally active inhibitor targeting MMP-2, MMP-9, and MMP-13, exhibiting potent inhibition with K_i values of 0.03, 0.01, and 0.03 nM, respectively. By inhibiting these metalloproteinases, SD-7300 effectively reduces extracellular matrix degradation by tumor cells, thereby curbing their invasion and metastasis. Additionally, this compound acts as a dose-dependent inhibitor of mouse corneal angiogenesis and prevents interleukin-1-induced degradation of bovine cartilage. SD-7300 is applicable in the study of breast cancer.

• Smiles :

  O=C(NO)C1(CCN(CCOC)CC1)S(=O)(=O)N2CCC(OC3=CC=C(OC(F)(F)F)C=C3)CC2

• Molecular Formula :

  C21H30F3N3O7S

• Molecular Weight :

  525.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  748120-89-0