SD-70

• Target :

  Histone Demethylase

• Related Pathways :

  Chromatin/Epigenetic

• Bioactivity :

  SD-70, an inhibitor of the demethylase JMJD2C, exhibits antitumor activity. It inhibits the proliferation of cancer cells in CWR22Rv1 (10 ?M, 9% cell viability), PC3 (2 ?M, 14% cell viability), and DU145 (2 ?M, 26% cell viability) .

• Smiles :

  O=C(NC(C=1OC=CC1)C=2C=CC3=CC=CN=C3C2O)C(C)C

• Molecular Formula :

  C18H18N2O3

• Molecular Weight :

  310.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  332173-89-4