MK-3168 (12C)

• Target:

  FAAH

• Related Pathways:

  Neuroscience|||Metabolism

• Bioactivity:

  MK-3168 (12C) functions as a FAAH inhibitor, exhibiting IC50 values of 1.0 nM, 5.5 nM, and 1.7 nM for human, rhesus, and rat respectively. It demonstrates effective brain uptake and FAAH-specific signaling. Additionally, 11 C MK-3168 is applicable as a FAAH PET tracer.

• Smiles:

  C(N(C)C)(=O)[C@@H]1[C@H](C1)C2=CC=C(C=C2)C3=C(SC4=CC=C(Cl)C=N4)N(C)C=N3

• Molecular Formula:

  C21H21ClN4OS

• Molecular Weight:

  412.94

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1242441-26-4