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JNK-1-IN-3

CAT: 0931-T200221-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T200221-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3056388-71-4
Target
MMP, JNK, p53
Related Pathways
Proteases/Proteasome, Apoptosis, MAPK
Purity
0.97551
Bioactivity
JNK-1-IN-3 (Compound 9e) is a JNK1 inhibitor that downregulates JNK1 and phosphorylated JNK1, reduces c-Jun and c-Fos expression in tumours, and restores p53 activity. JNK-1-IN-3 exhibits potent antiproliferative activity against renal carcinoma and breast cancer cell lines.
Smiles
O=C(NNC=1N=NC(=CC1)C2=CC=C(OC)C(OC)=C2)C3=CC=C(F)C=C3
Molecular Formula
C19H17FN4O3
Molecular Weight
368.36
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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