JNK-1-IN-1

• UNSPSC Description:

  JNK-1-IN-1 is a JNK-1 inhibitor. JNK-1-IN-1 also inhibits MKK7 with an IC50 of 7.8μM. JNK-1-IN-1 bind to MKK7cp and acts as an inhibitor of JNK-1[1].

• Target Antigen:

  JNK

• Type:

  Reference compound

• Related Pathways:

  MAPK/ERK Pathway

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/jnk-1-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CCCN(C1=NC(C=CC=C2)=C2S1)CC(C=C3)=CC=C3C4=CC=CC=C4C5=NNN=N5

• Molecular Weight:

  426.54

• References & Citations:

  [1]Comess KM, et al. Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases. ACS Chem Biol. 2011 Mar 18;6(3):234-44.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1262406-02-9