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ESI1

CAT: 0931-T200212-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T200212-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Endogenous Metabolite
Related Pathways
Metabolism
Bioactivity
ESI1 is a small molecule inhibitor of epigenetic silencing. This compound induces the formation of nuclear aggregates of the key lipid metabolism regulator SREBP1/2, thereby concentrating transcription co-activators to drive lipid/cholesterol biosynthesis. Additionally, ESI1 promotes myelin regeneration in demyelination animal models and facilitates de novo myelination on regenerating CNS axons, reversing age-related cognitive decline.
Smiles
O=C(NC1=C(N)C=CC=C1)C(C=N2)=NC=C2NCC3=CC=CC=C3.Cl
Molecular Formula
C18H18ClN5O
Molecular Weight
355.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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