ESI-08

• Target:

  CAMP|||Ras

• Related Pathways:

  MAPK|||GPCR/G Protein

• Purity:

  0.9905

• Bioactivity:

  ESI-08 is an effective antagonist of EPAC2 with an IC50 of 8.4 ?M. ESI-08 selectively blocks cAMP-induced EPAC activation but not cAMP-mediated PKA activation.

• Smiles:

  Cc1ccc(C)c(CSc2nc(C3CCCCC3)c(C#N)c(=O)[nH]2)c1

• Molecular Formula:

  C20H23N3OS

• Molecular Weight:

  353.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  301177-43-5