HC-5404-Fu

• CAS Number :

  3034479-99-4

• Target :

  PERK

• Related Pathways :

  Apoptosis

• Bioactivity :

  HC-5404-Fu is an inhibitor of PERK with anti-tumor activity. This compound inhibits the signaling pathway of the endoplasmic reticulum stress response. Additionally, HC-5404-Fu increases the sensitivity of renal cell carcinoma cells to vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitors (TKIs) . It holds potential for research into renal cell carcinoma, stomach cancer, metastatic breast cancer, small cell lung cancer, and other solid tumors.

• Smiles :

  C(=C/C(O)=O)\C(O)=O.CC1=C(C=2C=C(C(NC(C)C)=O)C(N)=NC2)C=CC(NC([C@H](O)C3=CC(F)=CC(F)=C3)=O)=C1

• Molecular Formula :

  C28H28F2N4O7

• Molecular Weight :

  570.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C