HC-5404-Fu

CAT: 0931-MF-0142429-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0142429-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3034479-99-4
Target
PERK
Related Pathways
Apoptosis
Bioactivity
HC-5404-Fu is an inhibitor of PERK with anti-tumor activity. This compound inhibits the signaling pathway of the endoplasmic reticulum stress response. Additionally, HC-5404-Fu increases the sensitivity of renal cell carcinoma cells to vascular endothelial growth factor (VEGF) receptor tyrosine kinase inhibitors (TKIs) . It holds potential for research into renal cell carcinoma, stomach cancer, metastatic breast cancer, small cell lung cancer, and other solid tumors.
Smiles
C(=C/C(O)=O)\C(O)=O.CC1=C(C=2C=C(C(NC(C)C)=O)C(N)=NC2)C=CC(NC([C@H](O)C3=CC(F)=CC(F)=C3)=O)=C1
Molecular Formula
C28H28F2N4O7
Molecular Weight
570.54
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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