KT-474

• Target :

  PROTACs|||Apoptosis|||IRAK

• Related Pathways :

  Apoptosis|||NF-?B|||Immunology/Inflammation|||PROTAC

• Purity :

  0.9957

• Bioactivity :

  KT-474 (KYM-001) is a PROTAC degrader targeting interleukin-1 receptor-associated kinase 4 (IRAK4) with antitumor activity for the study of autoimmune, inflammatory, and cardiovascular disease disorders.

• Smiles :

  O=C1N(C=2C(=C(C#CCOC3CCN(C[C@H]4CC[C@@H](CC4)N5C=C(NC(=O)C6=C7N(N=C6)C=CC(=N7)N8[C@@]9(C[C@](C8)(OC9)[H])[H])C(C(F)F)=N5)CC3)C=CC2)N1C)C%10C(=O)NC(=O)CC%10

• Molecular Formula :

  C44H49F2N11O6

• Molecular Weight :

  865.93

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2432994-31-3