KT-474

CAT: 0931-T74411-01Size: 1 mgDry Ice: NoHazardous: No

CAT#:0931-T74411-01Size:1 mg

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PRICE

AVAILABILITY

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

1 / 1

CAS Number

2432994-31-3

Target

PROTACs|||Apoptosis|||IRAK

Related Pathways

Apoptosis|||NF-?B|||Immunology/Inflammation|||PROTAC

Purity

0.9957

Bioactivity

KT-474 (KYM-001) is a PROTAC degrader targeting interleukin-1 receptor-associated kinase 4 (IRAK4) with antitumor activity for the study of autoimmune, inflammatory, and cardiovascular disease disorders.

Smiles

O=C1N(C=2C(=C(C#CCOC3CCN(C[C@H]4CC[C@@H](CC4)N5C=C(NC(=O)C6=C7N(N=C6)C=CC(=N7)N8[C@@]9(C[C@](C8)(OC9)[H])[H])C(C(F)F)=N5)CC3)C=CC2)N1C)C%10C(=O)NC(=O)CC%10

Molecular Formula

C44H49F2N11O6

Molecular Weight

865.93

Shipping Conditions

Cool pack

Storage Temperature

-20°C

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KT-474

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