Antibacterial agent 236

• Target :

  Antibacterial|||Topoisomerase

• Related Pathways :

  DNA Damage/DNA Repair|||Microbiology/Virology

• Bioactivity :

  Anti bacterial agent 236 (Compound 4l), an orally effective inhibitor of DNA gyrase and topoisomerase IV (with IC50 values of 3.2 and 300 nM in Staphylococcus aureus, respectively), exhibits broad-spectrum antibacterial activity. It also demonstrates favorable pharmacokinetic properties in mice.

• Smiles :

  N#CC=1C=CC=2C=CC(=O)N(C2C1)CCN3CCC(NCC4=CC=C5SCC(=O)NC5=C4)CC3

• Molecular Formula :

  C26H27N5O2S

• Molecular Weight :

  473.59

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2364479-10-5