Bz-FVR-AMC (TFA)

Bz-FVR-AMC (TFA)

• UNSPSC Description: Bz-FVR-AMC TFA is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM-1s-1. The high concentration of BZ-FVR-AMC inhibits the substrate[1][2].
• Target Antigen: Cathepsin
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/bz-fvr-amc-tfa.html
• Smiles: CC1=CC(OC2=CC(NC([C@@H](NC([C@H](C(C)C)NC([C@@H](NC(C3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)CCCNC(N)=N)=O)=CC=C12)=O.O=C(O)C(F)(F)F.[x]
• Molecular Weight: 681.78(free base)
• References & Citations: [1]Vasiljeva O, et al. Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans. FEBS Lett. 2005 Feb 14;579(5):1285-90.|[2]Vasiljeva O, et al. Recombinant human cathepsin H lacking the mini chain is an endopeptidase. Biochemistry. 2003 Nov 25;42(46):13522-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported