Bz-FVR-AMC (TFA)

CAT: 0804-HY-D1634ASize: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-D1634ASize:1 Each

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Description

Bz-FVR-AMC TFA is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM-1s-1. The high concentration of BZ-FVR-AMC inhibits the substrate[1][2].

UNSPSC

12171500

Target

Cathepsin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/bz-fvr-amc-tfa.html

Smiles

CC1=CC(OC2=CC(NC([C@@H](NC([C@H](C(C)C)NC([C@@H](NC(C3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)CCCNC(N)=N)=O)=CC=C12)=O.O=C(O)C(F)(F)F.[x]

Molecular Formula

.xCF3COOH.xCF3COOH

Molecular Weight

681.78 (free base)

References & Citations

[1]Vasiljeva O, et al. Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans. FEBS Lett. 2005 Feb 14;579 (5) :1285-90.|[2]Vasiljeva O, et al. Recombinant human cathepsin H lacking the mini chain is an endopeptidase. Biochemistry. 2003 Nov 25;42 (46) :13522-8.

Shipping Conditions

Room temperature

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

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Bz-FVR-AMC (TFA)

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