Boc-GRR-AMC (TFA)

• UNSPSC Description:

  Boc-GRR-AMC (TFA) is a tri-peptide Substrate. Boc-GRR-AMC can be used for a fluorogenic West Nile virus (WNV) substrate, profiling the substrate specificity for the NS2B-NS3 proteases or determining the pH optimum of LdMC activity[1][2].

• Target Antigen:

  Others

• Type:

  Peptides

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/boc-grr-amc-tfa.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC(CNC(OC(C)(C)C)=O)=O)=O)=O)C=C1O2)=CC2=O.OC(C(F)(F)F)=O.[x]

• Molecular Weight:

  644.72 (free base)

• References & Citations:

  [1]Nancy Lee, et al. Characterization of metacaspases with trypsin-like activity and their putative role in programmed cell death in the protozoan parasite Leishmania. Eukaryot Cell. 2007 Oct;6(10):1745-57.|[2]Manolya Ezgimen, et al.Characterization of the 8-hydroxyquinoline scaffold for inhibitors of West Nile virus serine protease. Antiviral Res. 2012 Apr;94(1):18-24.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported