Bz-FVR-AMC

• UNSPSC Description:

  Bz-FVR-AMC is a fluorogenic substrate for procathepsin with a kcat/Km value of 1070 mM-1s-1. The high concentration of BZ-FVR-AMC inhibits the substrate[1][2].

• Target Antigen:

  Cathepsin

• Type:

  Dye Reagents

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/bz-fvr-amc.html

• Purity:

  99.83

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  CC1=CC(OC2=CC(NC([C@@H](NC([C@H](C(C)C)NC([C@@H](NC(C3=CC=CC=C3)=O)CC4=CC=CC=C4)=O)=O)CCCNC(N)=N)=O)=CC=C12)=O

• Molecular Weight:

  681.78

• References & Citations:

  [1]Vasiljeva O, et al. Recombinant human procathepsin S is capable of autocatalytic processing at neutral pH in the presence of glycosaminoglycans. FEBS Lett. 2005 Feb 14;579(5):1285-90.|[2]Vasiljeva O, et al. Recombinant human cathepsin H lacking the mini chain is an endopeptidase. Biochemistry. 2003 Nov 25;42(46):13522-8.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  88899-22-3