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Recombinant human OSTF1 protein

CAT: 0112-OSF0905-020Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0112-OSF0905-020Size:20 µg
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Description
Osteoclast-stimulating factor-1 (OSTF1) is an intracellular protein produced by osteoclasts that indirectly induces osteoclast (OCL) formation and bone resorption. OSTF1 is highly expressed in OCL and contains structural domains such as SH3 and ankyrin repeats, which are potentially involved in protein-protein interactions. OSTF1 is ubiquitously expressed analogous to other regulators of OCL activity such as c-Src or transforming growth factor beta. Recombinant human OSTF1 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Osteoclast stimulating factor 1, SH3P2, OSF, Osteoclast stimulating factor 1
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by Bradford assay)
Purity
> 95% by SDS-PAGE
Molecular Weight
25.1 kDa (225aa) confirmed by MALDI-TOF
Additionnal Information
OSTF1, Osteoclast stimulating factor 1, SH3P2, OSF, Osteoclast stimulating factor 1, OSF0905-10 µg, OSF0905-20 µg, OSF0905-50 µg, OSF0905-100 µg, OSF0905-250 µg, OSF0905-500 µg, OSF0905-1 mg, OSF0905-10, OSF0905-20, OSF0905-50, OSF0905-100, OSF0905-250, OSF0905-500, OSF0905-1
References & Citations
Kurihara N., et al. (2001) J Bio Chem. 276 (44) :41035-9; ; Reddy S., et al. (1998) Cell Physiol. 177 (4) :636-45.;
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.5mM DTT, 10% glycerol
Scientific Category
Hormones & Cytokines
NCBI Accession Number
AAH07459
Uniprot Accession Number
Q92882
Species
Human
AA Sequence
MSKPPPKPVK PGEGGQVKVF RALYTFEPRT PDELYFEEGD IIYITDMSDT NWWKGTSKGR TGLIPSNYVA EQAESIDNPL HEAAKRGNLS WLRECLDNRV GVNGLDKAGS TALYWACHGG HKDIVEMLFT QPNIELNQQN KLGDTALHAA AWKGYADIVQ LFLAKGARTD LRNIEKKLAF DMATNAACAS LLKKKQGTDA VRTLSNAEDY LDDEDSDLEH HHHHH

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