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Recombinant human RCAN2 protein

CAT: 0112-ATGP1309-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP1309-100Size:100 µg
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Description
Calcipressin-2, also known as RCAN2, belonging to the RCAN (Regulator of calcineurin) family modulate the activity of Calcineurin through a valine-rich region within their carboxyl tail. RCANs compete with NFAT (nuclear factor of activated T-cells) for binding to the same docking site in calcineurin, which results in either inhibition or activation of calcineurin activity. RCAN2 is a Ca (2+) dependent protein phosphatase that is involed in several neuornal functions. Recombinant human RCAN2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
Calcipressin-2, CSP2, DSCR1L1, hRCN2, MCIP2, RCN2, ZAKI-4, ZAKI4
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
0.5 mg/mL (determined by Bradford assay)
Purity
> 85% by SDS-PAGE
Molecular Weight
24.1 kDa (217aa) confirmed by MALDI-TOF
Additionnal Information
RCAN2, Calcipressin-2, CSP2, DSCR1L1, hRCN2, MCIP2, RCN2, ZAKI-4, ZAKI4, ATGP1309-10 µg, ATGP1309-20 µg, ATGP1309-50 µg, ATGP1309-100 µg, ATGP1309-250 µg, ATGP1309-500 µg, ATGP1309-1 mg, ATGP1309-10, ATGP1309-20, ATGP1309-50, ATGP1309-100, ATGP1309-250, ATGP1309-500, ATGP1309-1
References & Citations
Qin L., et al. (2006) Mal Cancer Res. 4:811-820.; ; Porta S., et al. (2007) Eur J Neurosci. 26:1213-1226.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.2M NaCl
Scientific Category
Signal Transduction
NCBI Accession Number
NP_005813
Uniprot Accession Number
Q14206
Species
Human
AA Sequence
MGSSHHHHHH SSGLVPRGSH MPAPSMDCDV STLVACVVDV EVFTNQEVKE KFEGLFRTYD DCVTFQLFKS FRRVRINFSN PKSAARARIE LHETQFRGKK LKLYFAQVQT PETDGDKLHL APPQPAKQFL ISPPSSPPVG WQPINDATPV LNYDLLYAVA KLGPGEKYEL HAGTESTPSV VVHVCDSDIE EEEDPKTSPK PKIIQTRRPG LPPSVSN

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