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Recombinant human ROBLD3/LAMTOR2 protein

CAT: 0112-ATGP0834-100Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0112-ATGP0834-100Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ROBLD3, also known as MAPBPIP, belongs to the GAMAD family. It is an adapter protein that enhances the efficiency of the MAP kinase cascade and facilitates the activation of MAPK2. ROBLD3 compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes. Recombinant human ROBLD3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Product Name Alternative
ENDAP, Endosomal adaptor protein p14, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2, MAPBP-interacting protein, MAPBPIP, MAPKSP1 adaptor protein, MAPKSP1AP, Mitogen activated protein binding protein interacting protein, p14, Ragulator complex protein LAMTOR2, Ragulator2, Roadblock domain containing 3
Expression System
E.coli
Antigen Species
Human
Tag
His-Tag
Applications
SDS-PAGE
Concentration
1 mg/mL (determined by BCA)
Purity
> 95% by SDS-PAGE
Molecular Weight
16 kDa (149aa) confirmed by MALDI-TOF
Additionnal Information
ENDAP, Endosomal adaptor protein p14, HSPC003, LAMTOR2, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2, MAPBP-interacting protein, MAPBPIP, MAPKSP1 adaptor protein, MAPKSP1AP, Mitogen activated protein binding protein interacting protein, Mitogen-activated protein-binding protein-interacting protein, p14, Ragulator complex protein LAMTOR2, Ragulator2, Roadblock domain containing 3, ROBLD3, RP11-336K24.9, ATGP0834-10 µg, ATGP0834-20 µg, ATGP0834-50 µg, ATGP0834-100 µg, ATGP0834-250 µg, ATGP0834-500 µg, ATGP0834-1 mg, ATGP0834-010, ATGP0834-020, ATGP0834-050, ATGP0834-100, ATGP0834-250, ATGP0834-500, ATGP0834-01M
References & Citations
Sancak Y., et al. (2010) Cell. 141 (2) :290-303.; ; Waters S., et al. (2009) FEBS Lett. 583 (12) :1846-52.
Storage Conditions
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Formulation
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M Nacl, 10% glycerol
Scientific Category
Signal Transduction
NCBI Accession Number
NP_054736.1
Uniprot Accession Number
Q9Y2Q5
Species
Human
AA Sequence
MLRPKA LTQVLSQANT GGVQSTLLLN NEGSLLAYSG YGDTDARVTA AIASNIWAAY DRNGNQAFNE DNLKFILMDC MEGRVAITRV ANLLLCMYAK ETVGFGMLKA KAQALVQYLE EPLTQVAAS

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