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3,4,5-Trichlorophenylboronic acid

CAT: 1139-862248-93-9Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1139-862248-93-9Size:1 Each
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Description
3,4,5-Trichlorophenylboronic acid (CAS 862248-93-9) is a high-purity trichlorinated aromatic boronic acid fine chemical with unique electron-withdrawing molecular properties and excellent reaction activity. This compound features three chlorine substituents on the benzene ring, presenting strong structural stability and moderate moisture sensitivity. It is slightly soluble in conventional organic solvents, with stable physical and chemical properties under low-temperature inert storage conditions. 3,4,5-Trichlorophenylboronic acid (CAS 862248-93-9) is a core halogenated boronic acid building block, widely utilized in organic synthesis, pharmaceutical intermediate derivation and functional material modification in fine chemical industrial production.
HS Code
2931900090
Applications
1. Suzuki Cross-Coupling Organic Synthesis: 3,4,5-Trichlorophenylboronic acid (CAS 862248-93-9) serves as a high-activity monomer for Suzuki-Miyaura cross-coupling reactions. The trichlorinated electron-withdrawing structure optimizes reaction selectivity and molecular activity, enabling efficient synthesis of high-purity polychlorinated biaryl intermediates and supporting batch industrial synthesis of high-value fine chemical derivatives. 2. Pharmaceutical Intermediate Preparation: 3,4,5-Trichlorophenylboronic acid (CAS 862248-93-9) is an important modular intermediate for innovative drug research and development. The trichlorinated aromatic skeleton can effectively enhance the metabolic stability and biological activity of drug molecules, which is widely applied in the synthesis of antibacterial, anti-tumor and heterocyclic therapeutic drug intermediates. 3. Functional Material Structural Modification: 3,4,5-Trichlorophenylboronic acid (CAS 862248-93-9) is commonly used for the modification of polymer materials and organic functional materials. Its multi-chlorine substituted structure improves the flame retardancy, weather resistance and chemical corrosion resistance of target materials, meeting high-standard industrial material customization requirements. 4. Laboratory Synthetic Process Research: 3,4,5-Trichlorophenylboronic acid (CAS 862248-93-9) acts as a standard high-purity laboratory reagent. With stable batch consistency and controllable reaction activity, it is widely used for reaction mechanism verification and process optimization of multi-halogenated boronic acid compounds in scientific research experiments.
Purity
98%
Molecular Formula
C6H4BCl3O2
Molecular Weight
225.26
Shelf Life
2 years under proper storage
Appearance
White to off-white solid powder
Grade
Laboratory Grade, Industrial Grade
Density
1.60±0.1 g/cm3
Melting Point
>300°C
Boiling Point
379.1±52.0°C at 760 mmHg