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3,5-DIIODO-4-HYDROXYBENZOIC ACID

CAT: 1139-618-76-8-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-618-76-8-01Size:10 g
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Description
3,5-DIIODO-4-HYDROXYBENZOIC ACID (CAS 618-76-8), also known as Ioxynic acid, is a high-activity diiodo-substituted hydroxybenzoic acid fine chemical intermediate. The molecular structure contains carboxyl group, phenolic hydroxyl group and two iodine substitution sites, possessing multiple active functional groups for diversified derivatization. The diiodo substitution structure enhances molecular lipophilicity and chemical reactivity, while the phenolic hydroxyl and carboxyl groups provide excellent reaction activity for esterification, condensation and cross-coupling reactions. Featuring stable chemical properties, high product purity and controllable reaction performance, it is widely used in pharmaceutical API synthesis, biochemical research, cosmetic additive intermediates and organic fine chemical modification fields.
Synonyms
3,5-Diiodo-4-hydroxybenzoic acid, 4-Hydroxy-3,5-diiodobenzoic acid, Ioxynic acid, 3,5--4-
HS Code
2918290000
Applications
1. Pharmaceutical API & Biochemical Intermediates: 3,5-DIIODO-4-HYDROXYBENZOIC ACID (CAS 618-76-8) is a core synthetic raw material for thyroid hormone drugs, anti-inflammatory drugs and biochemical reagents. Its unique diiodophenolic acid structure can effectively simulate biological active structures, optimize drug molecular bioavailability and binding activity, and is widely used in the research, development and pilot production of endocrine regulatory drugs and targeted therapeutic small molecules. 2. Organic Synthesis & Cross-Coupling Reaction Monomer: 3,5-DIIODO-4-HYDROXYBENZOIC ACID (CAS 618-76-8) has highly active iodine leaving groups and dual hydrophilic functional groups (hydroxyl and carboxyl) . It can participate in Suzuki, Heck, Sonogashira and other metal-catalyzed cross-coupling reactions, as well as esterification and salt-forming reactions. It is commonly used for the directional synthesis of complex substituted aromatic derivatives and functional organic molecules, serving as an important foundational monomer for organic synthesis methodology research. 3. Cosmetic & Preservative Intermediate: 3,5-DIIODO-4-HYDROXYBENZOIC ACID (CAS 618-76-8) can be derivatized into high-efficiency antibacterial and antioxidant functional additives. The diiodo phenolic structure has excellent bacteriostatic and anti-oxidation properties, which can effectively inhibit microbial reproduction and delay material aging. It is applied in the synthesis of cosmetic preservatives, skin care functional additives and daily chemical raw materials. 4. Functional Material Modification Precursor: 3,5-DIIODO-4-HYDROXYBENZOIC ACID (CAS 618-76-8) is used for the modification and functionalization of polymer materials and resin materials. The reactive functional groups can graft and modify polymer molecular chains, effectively improving the thermal stability, antibacterial performance and chemical corrosion resistance of materials, meeting the preparation requirements of high-performance functional polymer materials.
Purity
98% Min / 99% High Purity (HPLC)
Molecular Formula
C7H4I2O3
Molecular Weight
389.91
Shelf Life
2 years under proper storage
Appearance
White to off-white crystalline powder
Grade
Pharmaceutical Intermediate Grade / Research Grade / Fine Chemical Grade
Density
2.697±0.06 g/cm3
Melting Point
228-232 °C
Boiling Point
380.8±42.0 °C (760 mmHg)
EINECS
210-555-2