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2,3,5-Trichlorophenylboronic acid

CAT: 1139-212779-19-6-01Size: 10 gDry Ice: NoHazardous: No
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CAT#:1139-212779-19-6-01Size:10 g
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Description
2,3,5-Trichlorophenylboronic acid (CAS: 212779-19-6) is a high-purity trichlorine-substituted aromatic boronic acid fine chemical intermediate. The molecular structure contains three chlorine atoms substituted at the 2, 3, and 5 positions of the benzene ring, featuring unique electron-withdrawing properties, stable molecular skeleton and high reaction selectivity. 2,3,5-Trichlorophenylboronic acid (CAS: 212779-19-6) has excellent thermal stability, low hydrolysis rate and few synthetic by-products under conventional reaction conditions. Its special halogen-substituted structure endows it with unique synthetic application value, widely used in industrial cross-coupling reactions, pesticide intermediate synthesis, pharmaceutical molecule modification and laboratory organic synthesis research.
Synonyms
2,3,5-Trichloro-benzeneboronic acid, 2,3,5-Trichloro phenylboronic acid, 3,5,2-Trichlorophenylboronic acid, Boronic acid, 2,3,5-trichlorophenyl-
Applications
1. Industrial Suzuki Cross-Coupling Synthesis Application: 2,3,5-Trichlorophenylboronic acid (CAS: 212779-19-6) is a core halogenated aromatic monomer for industrial Suzuki cross-coupling reactions. The trichlorine-substituted structure provides stable electron-withdrawing effects, improves reaction specificity, effectively reduces side reactions in continuous industrial production, and is used for large-scale synthesis of high-value trichlorinated biphenyl fine chemical derivatives. 2. Pesticide Intermediate Synthesis Application: 2,3,5-Trichlorophenylboronic acid (CAS: 212779-19-6) serves as a key intermediate for the R&D and production of high-efficiency pesticide intermediates. The multi-chlorine substituted benzene ring structure can significantly improve the biological activity and environmental adaptability of pesticide molecules, and is widely applied in the derivation of fungicides and insecticide intermediates. 3. Pharmaceutical Intermediate Modification Application: 2,3,5-Trichlorophenylboronic acid (CAS: 212779-19-6) is an important modified raw material for pharmaceutical synthesis. Its unique halogenated structure can adjust the lipophilicity, metabolic stability and molecular targeting of drug compounds, supporting the structural optimization of anti-infective and antitumor drug intermediates. 4. Laboratory Organic Synthesis Research Application: 2,3,5-Trichlorophenylboronic acid (CAS: 212779-19-6) is a standard experimental reagent for studying the reaction mechanism of multi-chlorine substituted phenylboronic acids, supporting the development of new halogenated organic compounds and the optimization of industrial synthetic process parameters.
Purity
98%
Molecular Formula
C6H4BCl3O2
Molecular Weight
225.27
Shelf Life
2 years under proper storage
Appearance
White to Off-white Crystalline Powder
Grade
Synthetic Grade / Research Grade / Fine Chemical Intermediate Grade
Density
1.58±0.1 g/cm3
Melting Point
278-282 °C