4-fluoroazepane hydrochloride

4-fluoroazepane hydrochloride (CAS: 1373502-66-9) is a fluorinated saturated seven-membered nitrogen heterocyclic hydrochloride salt. This compound is formed by salifying 4-fluoroazepane with hydrochloric acid, featuring excellent water solubility and stable chemical properties compared with free amine monomer. The fluorine substitution at the 4-position of azepane ring improves molecular lipophilicity and metabolic stability, while hydrochloride form effectively avoids amine oxidation and deterioration during storage. It is a commonly used fluorinated alicyclic amine building block for pharmaceutical intermediate synthesis and custom organic synthesis.

4-Fluoroazepane HCl, 4-fluoroazepanium chloride, Azepane, 4-fluoro-, hydrochloride

2933990090

1. Central Nervous System Drug Intermediates:4-fluoroazepane hydrochloride (CAS: 1373502-66-9) serves as a core heterocyclic raw material for CNS drug development. Its optimized lipophilicity helps drug molecules penetrate the blood-brain barrier, widely used in the synthesis of antidepressants and anxiety treatment drugs. 2. Organic Synthetic Amine Building Blocks: Organic synthesis laboratories adopt 4-fluoroazepane hydrochloride (CAS: 1373502-66-9) to conduct neutralization, Boc protection, alkylation and amide condensation reactions. It is a stable amine source for multi-step synthesis of complex nitrogen-containing heterocyclic derivatives. 3. Fluorinated Fragment Library Screening: 4-fluoroazepane hydrochloride (CAS: 1373502-66-9) is added to pharmaceutical small molecule fragment libraries for high-throughput drug screening, providing fluorinated azepane fragments to enhance target protein binding activity of lead compounds. 4. Anti-infective Drug Precursor Synthesis: This product is applied in the preparation of novel antibacterial and antiviral small molecule drugs. 4-fluoroazepane hydrochloride (CAS: 1373502-66-9) modifies drug molecular structure via fluorine atom to improve drug efficacy and reduce drug resistance.

≥98% (HPLC)

C6H13ClFN

153.63

2 years under proper storage

White crystalline powder

Pharmaceutical Intermediate Grade, Organic Synthesis Grade

1.07±0.06 g/cm3 (Predicted)

Not available