RN139 rabbit pAb

• Background :

  The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t (3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]

• Gene ID :

  11236

• Swiss Prot :

  Q8WU17

• Cross Reactivity :

  Human; Mouse

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB

• Dilution :

  WB 1: 500-2000

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Storage Conditions :

  -20°C/1 year