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RN139 Rabbit Polyclonal Antibody

CAT: 0965-JOT-AP12308-01Size: 20 µLDry Ice: NoHazardous: No
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CAT#:0965-JOT-AP12308-01Size:20 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum| and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL| as well as with COPS5/JAB1| a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP.
CAS Number
9007-83-4
Synonyms
RN139
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from human RN139
Clonality
Polyclonal
Applications
WB
Stability
-20°C for 1 year
Concentration
1 mg/ml
Molecular Weight
73040
Antibody Type
Primary antibody
Isotype
IgG