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PSD-95 Antibody

CAT: 0498-bs-70235RSize: 100 µLDry Ice: NoHazardous: No
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CAT#:0498-bs-70235RSize:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PSD-95 is a very prominent component of the postsynaptic densities of synapses. It contains three PDZ domains which play key roles in its interactions with other proteins in the synapse. It has been proposed that these PDZ domains organize glutamate receptors and their associated signaling proteins and determine the size and strength of synapses (Kim and Sheng, 2004) . Recent work suggests that interaction of the NMDAR with PSD-95 via these PDZ domains can be regulated by phosphorylation (Chung et al., 2004) .
Synonyms
Discs large homolog 4 antibody, Disks large homolog 4 antibody, DLG 4 antibody, Dlg4 antibody, DLG4_HUMAN antibody, FLJ97752 antibody, FLJ98574 antibody, Human post synaptic density protein 95 antibody, Post synaptic density protein 95 antibody, Postsynaptic density protein 95 antibody, PSD 95 antibody, PSD-95 antibody, PSD95 antibody, SAP 90 antibody, SAP-90 antibody, SAP90 antibody, Synapse associated protein 90 antibody, Synapse-associated protein 90 antibody, Tax interaction protein 15 antibody
Gene ID
29495
Swiss Prot
P31016
Host
Rabbit
Cross Reactivity
Mouse, Rat
Target
PSD-95
Clonality
Polyclonal
Isotype
IgG
Conjugation
Unconjugated
Source
Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat PSD-95, conjugated to keyhole limpet hemocyanin (KLH) .
Applications
WB
Purification
Antigen Affinity purification from Pooled whole antiserum
Concentration
Lot Dependent
Dilution
WB (1:300-5000)
Buffer
10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Modification
Unmodified
Storage Conditions
Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.
Specificity
Specific for endogenous levels of the ~95 kDa PSD-95 protein.
Gene ID URL
29495
Predicted Cross Reactivity
Human, Bovine, Zebrafish, Non-Human Primate