CSF1R-IN-1

• UNSPSC Description:

  CSF1R-IN-1 is a CSF1R inhibitor with an with an IC50 of 0.5 nM.

• Target Antigen:

  c-Fms

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/CSF1R-IN-1.html

• Purity:

  98.11

• Solubility:

  DMSO : 83.33 mg/mL (ultrasonic)

• Smiles:

  CC1=CC=C(NC(C2=CC=CC(C(F)(F)F)=C2)=O)C=C1NC(C3=CC(C4=CN(C)N=C4)=CN=C3)=O

• Molecular Weight:

  479.45

• References & Citations:

  [1]Ramachandran SA, et al. Design, synthesis and optimization of bis-amide derivatives as CSF1R inhibitors. Bioorg Med Chem Lett. 2017 May 15;27(10):2153-2160.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2095849-04-8